PICO fundamentally reminds us to chop our concepts into a few little words. Don't use natural language, especially sentences. Common words have the potential to eliminate results, without separating out the results you need. But other words and phrases are very distinctive, with an unmistakable meaning. Use those!
Word concepts:
synonyms, antonyms, related concepts
narrower, broader
more technical or insider language, more colloquial
keywords, subject headings
Optional -- 3:30 minute video on subject headings: CINAHL nursing theories, PubMed eating disorders
Example:
"social networks" (elderly OR older OR aging)
nursing
review, "systematic review"